The mystery behind the long-rumoured Will & Grace reunion has been solved … as the cast have released a special skit tackling the American presidential election.

Ten years after the show ended, fans were teased with days of cryptic tweets and photos before former co-stars Debra Messing, Eric McCormack, Sean Hayes and Megan Mullally unveiled the new scene.

In a sketch packed full of references to Brangelina, Ryan Lochte and Fifty Shades Of Grey, Will (Eric) and Grace (Debra) complain about Donald Trump – before Karen (Megan) bustles in to out herself as a Trump voter. She even claims to have helped him pick his wife Melania.

Karen is a Trump voter
Karen is a Trump voter (Vote Honey/YouTube)

There is no hope of persuading Karen, but everything changes when “unemployed, uneducated angry white man” Jack (Sean) walks through the door. “How can one unemployed white fella registered in Pennsylvania make a difference?” he asks.

In an impassioned speech in favour of Democrat candidate Hillary Clinton, Grace explains: “She’s going to appoint justices to the Supreme Court who are going to ensure your civil rights.”

Hillary Clinton.
(Carolyn Kaster/AP)

“Yeah, but I don’t like that she wears pants,” Jack responds.

The video is part of an effort to get Americans to “Vote, honey” – and, by the sounds of things, vote for Clinton.